Salmonella enterica serotype Typhimurium and S. Stanley Differ in Genomic Evolutionary Patterns and Early Immune Responses in Human THP-1 cell line and CD14+ Monocytes

Publication date: Available online 22 December 2018Source: Comparative Immunology, Microbiology and Infectious DiseasesAuthor(s): Chin-Chin Huang, Shao-Hung Wang, Li-Te Chin, Chang-Lin Huang, Li-Ting Sun, Chien-Shun Chiou, Pei-Chun Tu, Chishih ChuABSTRACTSalmonella Typhimurium and S. Stanley are the most prevalent serogroup B serovars to infect humans in Taiwan. The aim was to determine possible factors to influence the prevalence between S. Typhimurium and S. Stanley. Genotypes were determined by pulsed field gel electrophoresis (PFGE) analysis and the intracellular survival, phagocytosis, reactive oxygen species (ROS) production of human monocyte THP-1 cell and tumor necrosis factor-α(TNF-α), interleukin-6 (IL-6), and IL-1βexpression in peripheral blood CD14+ cells after infection wer...

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://bit.ly/2A8fAT6