The Application of a New Model-Based Iterative Reconstruction in Low-Dose Upper Abdominal CT

Publication date: Available online 17 January 2019

Source: Academic Radiology

Author(s): Yongjun Jia, Bingying Zhai, Taiping He, Yong Yu, Nan Yu, Haifeng Duan, Chuangbo Yang, Xirong Zhang

Rationale and Objectives

To compare upper abdominal computed tomography (CT) image quality of new model-based iterative reconstruction (MBIR) with low-contrast resolution preference (MBIR_NR40), conventional MBIR (MBIR_c), and adaptive statistical iterative reconstruction (ASIR) at low dose with ASIR at routine-dose.

Materials and Methods

Study included phantom and 60 patients who had initial and follow-up CT scans. For patients, the delay phase was acquired at routine-dose (noise index = 10 HU) for the initial scan and low dose (noise index = 20 HU) for the follow-up. The low-dose CT was reconstructed with 40% and 60% ASIR, MBIR_c, and MBIR_NR40, while routine-dose CT was reconstructed with 40% ASIR. CT value and noise measurements of the subcutaneous fat, back muscle, liver, and spleen parenchyma were compared using one-way ANOVA. Two radiologists used semiquantitative 7-scale (−3 to +3) to rate image quality and artifacts.

Results

The phantom study revealed superior low-contrast resolution with MBIR_NR40. For patient scans, the CT dose index for the low-dose CT was 3.00 ± 1.32 mGy, 75% lower than the 11.90 ± 4.75 mGy for the routine-dose CT. Image noise for the low-dose MBIR_NR40 images was significantly lower than the low-dose MBIR_c and ASIR images, and routine-dose ASIR images (p < 0.05). Subjective ratings showed higher image quality for low-dose MBIR_NR40, with lower noise, better low-contrast resolution for abdominal structures, and finer lesion contours than those of low-dose MBIR_c and ASIR images, and routine-dose ASIR images (p < 0.05).

Conclusion

MBIR_NR40 with low-contrast resolution preference provides significantly lower noise and better image quality than MBIR_c and ASIR in low-dose abdominal CT; significantly better objective and subjective image quality than the routine-dose ASIR with 75% dose reduction.

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