Diarrhea in an infant: food protein induced enterocolitis or very early onset inflammatory bowel disease

Food protein induced enterocolitis (FPIES) is a non-IgE mediated food allergy diagnosed in infants and toddlers presenting with severe vomiting and diarrhea leading to shock in 15% of cases. Consulting allergists should keep very-early onset inflammatory bowel disease (VEO-IBD), defined as IBD diagnosed in children 6 years of age or younger in the differential. IBD in this young age group tends to be more severe and is associated with immune dysregulation. (Source: Journal of Allergy and Clinical Immunology)

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