New graft manipulation strategies improved outcome of mismatched stem cell transplantation in children with primary immunodeficiencies

Mismatched stem cell transplantation is associated with high risk of graft loss, graft versus host disease (GvHD) and transplant related mortality (TRM). Alternative graft manipulation strategies have been employed over the last 11 years to reduce these risks. (Source: Journal of Allergy and Clinical Immunology)

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