Τρίτη 16 Οκτωβρίου 2018

Engulfment of mast cell secretory granules upon skin inflammation boosts dendritic cell migration and priming efficiency

Dudeck et al. demonstrate that MC granules are engulfed by DCs upon skin inflammation and actively shuttled to LNs. MC granule uptake boosts DC activation and T cell priming efficiency, thereby enhancing the inflammatory response. (Source: Journal of Allergy and Clinical Immunology)

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