[Immunotherapy in castration resistant prostate cancer.]

Authors: Miñana López B, Villacampa Aubá F, de Fata Chillón FR, Ancizu Markert FJ, García Cortés A, Doménech López P, Chiva San Román S, Velis Campillo JM, Díez-Caballero Alonso F, Robles García JE, Rosell Costa D, Pascual Piédrola JI Abstract We review the role of immunotherapy in castration resistant prostate cancer. Two immunotherapeutic strategies have been applied, isolated or in combination, either with each other or with other agents with demonstrated efficacy in this scenario that would play a role as immunomodulators: vaccines or monoclonal antibodies aimed to block immune response checkpoint inhibitors. Although CRPC presents, a priori, characteristics suggesting that immunotherapy may play a relevant role as a therapeutic strategy, its clinical application ha...

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