Exploring the relationship between Endothelin-1 and peripheral inflammation in multiple sclerosis

Identifying pathways linking neuroinflammation and neurodegeneration is essential to help prevent disability progression in people with multiple sclerosis (MS). Endothelin-1 (ET-1) is a potent vasoconstrictor thought to contribute to cerebral hypoperfusion and tissue damage in MS. Its link with the neuroinflammatory process remains poorly investigated. (Source: Journal of Neuroimmunology)

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