Isothiazolinones, methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI), are widely used preservatives in cosmetic, industrial and household products owing to their strong biocidal effects.1 Following an epidemic of contact allergy to MCI/MI (Kathon CG) and subsequent regulatory measures on the use of MCI/MI, the use of MI as a monopreservative has increased.
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