Fecal microbiota transplantation as a tool to treat and reduce susceptibility to disease in animals

Publication date: Available online 3 November 2018Source: Veterinary Immunology and ImmunopathologyAuthor(s): Megan C. NiederwerderAbstractFecal microbiota transplantation (FMT) is the process by which fecal microbiota are donated from a healthy individual and subsequently transplanted into a diseased or young individual. The mechanism by which FMT is effective is believed to be due to enhanced beneficial microbes, increased microbiome diversity, and restored normal flora. Beneficial gut microorganisms not only play a role in maintaining an intestinal barrier and metabolizing nutrients, but importantly, these microbes help regulate local and systemic immune function. Although FMT has been described for several centuries, only recently has it been utilized as a mainstream therapy in humans ...

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