Authors: Pezzolo E, Naldi L Abstract INTRODUCTION: Smoking is the single most important cause of preventable mortality worldwide. Besides being associated with major cardiovascular and bronchopulmonary diseases, and several cancers, it has been linked with a number of immune-related conditions, including psoriasis and psoriatic arthritis (PsA), with an effect on disease development, which may differ according to the condition considered. We aimed to summarise data on the role of smoking in the development and prognosis of psoriasis and PsA, pointing to the consequences in terms of disease management. Areas covered: Mechanisms, clinical manifestations and comorbidities associated with smoking in psoriasis and PsA were reviewed by searching Medline, Embase and Cochrane Library databa...
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