Sensitization refers to the presence of antibodies to human leukocyte antigens (HLA). The percentage calculated panel reactive antibody (CPRA) is a measure of sensitization with higher CPRA associated with increased unacceptable donor HLA, a smaller pool of potential donors, and longer waiting times for an HLA compatible donor.1 Sensitization rates in heart transplant candidates have increased with 1 in 5 patients having a CPRA>10% reported in the International Society of Heart and Lung Transplantation (ISHLT) registry. (Source: The Journal of Heart and Lung Transplantation)
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Παρασκευή 21 Δεκεμβρίου 2018
Impact of organ prioritization for immunological sensitization and waiting times for heart transplantation
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