Morbidity pattern and interferon gamma level in sickle cell anemia patients with autosplenectomy

Conclusion: This study showed a higher prevalence of infection and bone pain crisis among SCA patients with autosplenectomy than in SCA patients without autosplenectomy. It also showed comparable level of IFN-γ in the 2 groups of patients. Patients with autosplenectomy may benefit from early institution of drugs such as hydroxyurea to improve quality of life. (Source: Nigerian Journal of Clinical Practice)

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