Oral exposure to mite allergens: Sensitizer or tolerogenic?

In a recent article, Ba ïz et al1 reported on the presence of Der p 1 mite allergen in two-thirds of breast milk samples from French lactating mothers. Allergen levels in the milk were higher in mothers with a history of asthma or allergies, and children breast-fed by such mothers with high Der p 1 levels in the milk wer e at a significantly higher risk of asthma or allergic rhinitis when compared with children from mothers with low Der p 1 levels in the milk. In addition, a high amount of Der p 1 in the milk was associated with increased total serum IgE. (Source: Journal of Allergy and Clinical Immunology)

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