Scientists devise strategies to counteract T cell exhaustion in CAR T cancer therapies

(La Jolla Institute for Immunology) CAR T-cell therapies have saved lives in patients with blood cancers, but there has been a downside: T cells that enter solid tumors can stop working due to a phenomenon called T cell exhaustion.Now scientists at the La Jolla Institute of Immunology (LJI) have found a way of counteracting T cell exhaustion and making CAR T cell therapies more effective. (Source: EurekAlert! - Cancer)

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