The mTOR-p70s6k axis inhibits the biological function of tongue squamous cell carcinoma

Studies have demonstrated mammalian target of rapamycin (mTOR) and 70-kDa ribosomal S6 kinase (p70s6k) to be tumour suppressors in many cancers. These factors may have synergistic functions in tongue squamous cell carcinoma (TSCC), which is the most common malignant cancer in the oral region. We aimed to investigate the expression of the mTOR-p70s6k axis in TSCC patients and its biological function in TSCC cell lines.

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