Role of photobiomodulation on the activation of the Smad pathway via TGF-β in wound healing

Publication date: Available online 11 October 2018Source: Journal of Photochemistry and Photobiology B: BiologyAuthor(s): Dimakatso Mokoena, Sathish Sundar Dhilip Kumar, Nicolette N. Houreld, Heidi AbrahamseAbstractWound healing is an essential process in which the separated or destroyed tissue attempts to restore itself into its normal state. In some instances, healing is prolonged and remains stagnant in the inflammatory phase, and is referred to as a chronic wound. At a cellular and molecular level, many factors are required during the process of successful wound healing, such as cytokines, polypeptide growth factors and components of the extracellular matrix (ECM). Transforming growth factor-beta (TGF-β) is considered as one of the essential growth factors in wound healing. Working th...

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