Upregulated P-Rex1 exacerbates human airway smooth muscle hyperplasia in asthma

P-Rex1, a Rac-selective activator is aberrantly upregulated in airway smooth muscle of subjects with asthma compared to non-asthmatics, and augments cell proliferation, thus contributing to airway smooth muscle hyperplasia and remodeling in severe asthma.

from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader https://ift.tt/2QGhaS8