Growth failure in Crohn's disease children: may the first treatment have a role?

Authors: Capriati T, Bizzarri C, Dilillo A, Nobili V, Oliva S, Diamanti A Abstract INTRODUCTION: Growth failure in children is a frequent feature of childhood-onset Crohn's disease (CD) and stunting can persist into adulthood. Growth is an important outcome by which to judge the effectiveness of therapies in children; currently available studies in CD children have focused on the short-term impact of treatments on growth and there are limited data regarding the long-term effects of treatments upon growth. Areas covered: We designed the present article to review whether the first treatment performed in newly diagnosed CD children may have a role on the future growth course. We conducted a systematic literature search to identify relevant studies published on the PubMed database from...

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