Novel Use of Cryopreserved Ultra-Thick Human Amniotic Membrane for Management of Anophthalmic Socket Contracture

Purpose: To describe the use of cryopreserved ultra-thick human amniotic membrane for management of anophthalmic socket contracture. Methods: A chart review was performed to identify patients undergoing fornix reconstruction with cryopreserved ultra-thick human amniotic membrane for management of anophthalmic socket contracture. Patient demographics, disease etiology, and data regarding postoperative prosthesis fit and complications were collected. Results: The technique is described in 3 female patients with anophthalmic socket contracture who underwent fornix reconstruction using cryopreserved ultra-thick human amniotic membrane. All patients had excellent prosthesis fit at final follow up (range, 10–14 months). There were no clinically significant complications and no reoperations were performed. One pyogenic granuloma developed and was excised without affecting ocular prosthesis fit. Conclusions: Cryopreserved ultra-thick human amniotic membrane is easy to use, well tolerated, and produces good outcomes for management of anophthalmic socket contracture. Accepted for publication September 11, 2018. Each author declares no conflicts of interest, including financial, paid consulting, patent rights, and family or personal ownership in market companies related to this article. Address correspondence and reprint requests to Christine C. Nelson, M.D., F.A.C.S., Department of Ophthalmology and Visual Sciences, W. K Kellogg Eye Center, 1000 Wall St, Ann Arbor, MI 48105. E-mail: cnelson@med.umich.edu © 2018 by The American Society of Ophthalmic Plastic and Reconstructive Surgery, Inc., All rights reserved.

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