Aquatic animal viruses mediated immune evasion in their host

Publication date: Available online 15 December 2018Source: Fish & Shellfish ImmunologyAuthor(s): Fei Ke, Qi-Ya ZhangAbstractViruses are important and lethal pathogens that hamper aquatic animals. The result of the battle between host and virus would determine the occurrence of diseases. The host will fight against virus infection with various responses such as innate immunity, adaptive immunity, apoptosis, and so on. On the other hand, the virus also develops numerous strategies such as immune evasion to antagonize host antiviral responses. Here, We review the research advances on virus mediated immune evasions to host responses containing interferon response, NF-κB signaling, apoptosis, and adaptive response, which are executed by viral genes, proteins, and miRNAs from different aquatic ...

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