The prognostic value of immunoscore in patients with colorectal cancer: A systematic review and meta ‐analysis

The meta ‐analysis involving a total of 4689 colorectal cancer cases from eight studies. The immunoscore could be a useful prognostic marker in patients with colorectal cancer. AbstractThe tumor immune infiltrate, as recently evaluated with the immunoscore methodology, has been reported to be related to colorectal cancer (CRC) progression. Nevertheless, results varied from different studies. A meta ‐analysis was conducted to solve this problem. We collected data from included studies to evaluate the prognostic role of immunoscore in CRC patients on overall survival (OS) and disease‐free survival (DFS). MEDLINE, EMBASE, and Cochrane libraries were searched through 30 June 2018. Hazard ratio (HR) with 95% confidence intervals (95% CI) was pooled using a random‐effects model for OS an...

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