Τρίτη 6 Νοεμβρίου 2018

Immunosuppressive effects of the limonoid azadirachtin, insights on a nongenotoxic stress botanical, in flesh flies

Publication date: Available online 4 November 2018Source: Pesticide Biochemistry and PhysiologyAuthor(s): Moataza A. Dorrah, Amr A. Mohamed, El-Sayed H. ShaurubAbstractThe tetranortriterpenoid azadirachtin (Aza) is a well-known insect growth disruptor of plant origin. Although its actions on insects have been extensively studied; fragmentary reports are available from the immunological point of view. Therefore, in the present study, total (THC) and differential hemocyte counts (DHC), nodulation, phenoloxidase (PO) activity, immune-reactive lysozymes and inducible nitric oxide (NO) were assessed, as measures of immune responses, in Sarcophaga argyrostoma 3rd instars challenged individually with M. luteus or Aza, or in combination with both compared to the control larvae. THC was significant...

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