Maxillofacial Implications of Scleroderma and Systemic Sclerosis – A Case Report and Literature Review

Scleroderma is a group of autoimmune diseases characterized by increased collagen synthesis and deposition within connective tissue. The skin disease can be classified into two major groups: localized and systemic scleroderma. Localized scleroderma differs from systemic scleroderma in that it involves only the skin. Systemic scleroderma, also known as systemic sclerosis, may affect any organ system.1 Systemic sclerosis is often differentiated from localized scleroderma early by the development of Raynaud's phenomenon, or paroxysmal vasospasm induced by cold or stress, which is the first sign in the vast majority of systemic sclerosis cases.

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