Tyrosine-Rich Crystalloids in Pleomorphic Adenoma: a Rare Descriptive Case

Pleomorphic adenoma (PA) is the most common salivary gland neoplasm and has several peculiar histopathologic features, such as tyrosine-rich crystalloids (TRCs), which can be present in 2% of PA cases. A 58-year-old woman underwent surgery to excise a parotid gland lesion. The surgical sample measured 30 × 26 × 24 mm; hematoxylin and eosin slides implicated PA comprising neoplastic strands of epithelial–myoepithelial cells, with some duct-like structures scattered in abundant loose stroma with unusual basophilic flower-shaped structures.

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