Τετάρτη 24 Οκτωβρίου 2018

Transcriptome profiling reveals key roles of phagosome and NOD-like receptor pathway in spotting diseased Strongylocentrotus intermedius

Publication date: January 2019Source: Fish & Shellfish Immunology, Volume 84Author(s): Weijie Zhang, Zhimeng Lv, Chenghua Li, Yahui Sun, Huijie Jiang, Manxi Zhao, Xuelin Zhao, Yina Shao, Yaqing ChangAbstractSpotting disease is a common disease in the process of aquaculture and restocking of the sea urchin Strongylocentrotus intermedius and leads to mass mortality. To characterize the molecular processes and candidate genes related to spotting disease in S. intermedius, we conducted next-generation sequencing to assess the key genes/pathways in spotting diseased sea urchin (DUG) compared to healthy ones (HUG). A total of 321.1 million clean reads were obtained and assembled into 93,877 Unigenes with an N50 of 1185 bp, in which 86.48% of them matched to the genome sequence of the sea urchin ...

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